SubtiBank SubtiBank
dynA
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dynA

dynamin-like protein, mediates membrane fusion
Locus
BSU_22030
Isoelectric point
5.72
Molecular weight
137.16 kDa
Protein length
1193 aa Sequence Blast
Gene length
3582 bp Sequence Blast
Function
fusion of membranes
Product
dynamin-like protein
Essential
no
Synonyms
ypbR

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,312,529 2,316,110

Phenotypes of a mutant

  • sensitive to membrane stress-inducing antibiotics PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • mediates nucleotide independent membrane fusion in vitro PubMed
  • Domains

  • two separate dynamin-like subunits and GTPase domains PubMed
  • Cofactors

  • Mg(2 ) PubMed
  • Localization

  • associated to the membrane PubMed
  • membrane, forms foci at the site of septation PubMed
  • colocalizes with FtsZ PubMed
  • highly dynamic membrane-associated protein; upon membrane damage, DynA localizes into large and static assemblies PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
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    Biological materials

    Mutant

  • MGNA-A877 (ypbR::erm), available at the NBRP B. subtilis, Japan
  • BKE22030 (dynA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAAGTCTGAACCCCTTTG, downstream forward: _UP4_TAAAATTCAGTTGGCTTGTA
  • BKK22030 (dynA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAAGTCTGAACCCCTTTG, downstream forward: _UP4_TAAAATTCAGTTGGCTTGTA
  • References

    Reviews

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    Original publications

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