function
biosynthesis of menaquinone
product
naphthoate synthase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.8|Biosynthesis of menaquinone][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|essential genes], [SW|phosphoproteins]Gene
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)Protein family
enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)Modification
phosphorylated on Arg-78 and Arg-269 [Pubmed|22517742]Structure
[PDB|1RJM] (from ''Mycobacterium tuberculosis'', 48% identity, 61% similarity)Expression and Regulation
Operon
''[protein|search|menF]-[protein|search|menD]-[protein|search|ytxM]-[protein|search|menB]-[protein|search|menE]-[protein|search|menC]'' [Pubmed|9387221,1629163,8550504]''[protein|search|menB]-[protein|search|menE]-[protein|search|menC]'' [Pubmed|9387221,1629163][SW|Sigma factor]
''[protein|search|menF]'': [protein|search|SigA] [Pubmed|8550504]''[protein|search|menB]'': [protein|search|SigA] [Pubmed|9387221,1629163]References
9387221,1629163,8550504,22517742 
