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bacC [2017-05-17 11:50:58]
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bacC [2017-05-17 11:50:58]

bacilysin biosynthesis oxidoreductase
Locus
BSU37720
Isoelectric point
4.96
Molecular weight
27.17 kDa
Protein length
255 aa Sequence Blast
Gene length
765 bp Sequence Blast
Function
biosynthesis of the antibiotic bacilysin
Product
bacilysin biosynthesis oxidoreductase
Essential
no
Synonyms
ywfD,ipa-82d

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,872,105 → 3,872,872

The protein

Catalyzed reaction/ biological activity

  • oxidation of the C(7)-hydroxyl, penultimate step in bacilysin biosynthesis PubMed
  • Protein family

  • short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s)

    Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • CodY: repression, PubMed, in CodY regulon
  • AbrB: repression, PubMed, in AbrB regulon
  • ScoC: repression, PubMed, in ScoC regulon
  • Regulation

  • expression of the operon is strongly induced at the beginning of biofilm formation PubMed
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    Biological materials

    Mutant

  • MGNA-B669 (ywfD::erm), available at the NBRP B. subtilis, Japan
  • References

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