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dacC [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
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dacC [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
locus
BSU18350
pI
5.00
mw
52.00 kDa
function
carboxypeptidase
product
penicillin-binding protein 4A,
D-alanyl-D-alanine carboxypeptidase
essential
no
synonyms
pbp
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.7|Penicillin-binding proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|penicillin-binding proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigH regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,998,340 -> 1,999,815

    The protein

    Catalyzed reaction/ biological activity

  • cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan [Pubmed|19758330]

    • Structure

  • [PDB|1W5D], [PDB|2J9P] (complex with a peptidoglycan mimetic peptide)

    • [SW|Interactions]

  • may be part of the [SW|cell wall biosynthetic complex] [Pubmed|17981078]

    • Expression and Regulation

    Operon

  • ''[protein|search|galM]-[protein|search|dacC]'' [Pubmed|9733705]

    • [SW|Sigma factor]

  • [protein|search|SigH] [Pubmed|9733705], [protein|search|SigB] [Pubmed|10482513]

    • References

    Reviews

  • 18266855

    • Original publications

  • 9733705,10482513,19758330,14731276,17582436,9864321,21821766,22029692,23560856,26460848