aimP

Viral quorum sensor, Phage SPbeta lysogeny promoter

Locus: BSU_20850

Isoelectric point: 6.26

Molecular weight: 4.08 kDa

Protein length: 41 aa

Gene length: 126 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: AimP,yopL

Genomic Context

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Categories containing this gene/protein

• Prophages and mobile genetic elements → Prophages → SP-beta prophage

Gene

Coordinates: 2,208,855 2,208,980

The protein

Catalyzed reaction/ biological activity

• Proteolytically cleaved in extracellular space to yield hexapeptide (GMPRGA) regulator. Hexapeptide re-enters cells and binds to AimR to promote SPbeta lysogeny. (PubMed)

Structure

• Hexapeptide bound to AimR: 5Y24 (PubMed), 5ZW6 (PubMed), 6IM4 (PubMed), 6HP5 (PubMed), 6JG9 (PubMed)

Expression and Regulation

Operons

• Genes: aimP
  Description: PubMed

  Regulatory mechanism

  • CcpA: repression, CcpA: transcription repression PubMed, in CcpA regulon

Biological materials

Mutant

• BKE20850 (aimP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTGTCTCACCTCCTTTAA, downstream forward: _UP4_TAAAATCCATTGACACATAA
• BKK20850 (aimP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTGTCTCACCTCCTTTAA, downstream forward: _UP4_TAAAATCCATTGACACATAA

References

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