SubtiBank SubtiBank
tcyA
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tcyA

cystine and diaminopimelate ABC transporter (binding protein)
Locus
BSU_03610
Isoelectric point
9.12
Molecular weight
29.32 kDa
Protein length
268 aa Sequence Blast
Gene length
807 bp Sequence Blast
Function
cystine uptake
Product
cystine and diaminopimelate ABC transporter (binding protein)
Essential
no
Synonyms
yckK
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → ABC transporters → Importers → Uptake of amino acids
  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of cysteine
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    410,656 411,462

    The protein

    Catalyzed reaction/ biological activity

  • uptake of cystine and diaminopimelate PubMed

    • Protein family

  • bacterial solute-binding protein 3 family (according to UniProt)

    • Paralogous protein(s)

  • YckB

    • Structure

  • 2YLN (from Neisseria gonorrhoeae, 54% identity) PubMed

    • Localization

  • attached to the membrane via TcyB PubMed

    • Expression and Regulation

    Operons

    Genes
    tcyA-tcyB-tcyC
    Description
    PubMed

    Regulation

  • strongly repressed in response to glucose starvation in M9 medium PubMed
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    Biological materials

    Mutant

  • BKE03610 (tcyA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTATTCCCCACTTTTC, downstream forward: _UP4_GAAGATGTTTCTAAATAATC
  • BKK03610 (tcyA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTATTCCCCACTTTTC, downstream forward: _UP4_GAAGATGTTTCTAAATAATC

    • References

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