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gcvPB [2018-03-18 11:58:17]
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gcvPB [2018-03-18 11:58:17]

glycine decarboxylase (subunit 2)
Locus
BSU24550
Isoelectric point
5.28
Molecular weight
54.26 kDa
Protein length
488 aa Sequence Blast
Gene length
1464 bp Sequence Blast
Function
glycine utilization
Product
glycine decarboxylase (subunit 2)
Essential
no
E.C.
1.4.4.2
Synonyms
yqhK,gcvP
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of threonine/ glycine

    • Gene

    Coordinates
    2,545,410 → 2,546,876

    The protein

    Catalyzed reaction/ biological activity

  • Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)

    • Protein family

  • C-terminal subunit subfamily (according to Swiss-Prot)

    • Localization

  • membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    gcvT-gcvPA-gcvPB
    Description
    PubMed

    Regulatory mechanism

  • Gly-box: termination, PubMed, in Gly-box

    • Regulation

  • induced by glycine PubMed
  • the Gly-box RNA is degraded by RNase Y PubMed
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    Biological materials

    Mutant

  • MGNA-C470 (yqhK::erm), available at the NBRP B. subtilis, Japan
  • BKE24550 (ΔgcvPB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCAAAAATAAGTGCCTGGT, downstream forward: _UP4_TAAATAAAAACAGCTGTCTA
  • BKK24550 (ΔgcvPB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCAAAAATAAGTGCCTGGT, downstream forward: _UP4_TAAATAAAAACAGCTGTCTA

    • References

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