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acpS [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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acpS [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

acyl-carrier protein synthase, 4-phosphopantetheine transferase
locus
BSU04620
pI
9.92
mw
13.00 kDa
function
fatty acid biosynthesis
product
acyl-carrier protein synthase
essential
yes
ec
2.7.8.7
synonyms
ydcB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of lipids], [SW|essential genes]

    • Gene

    Coordinates on the chromosome (coding sequence)
    515,710 -> 516,075

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein] (according to Swiss-Prot)

    • Protein family

  • AcpS family (according to Swiss-Prot)

    • [SW|Cofactors]

  • magnesium [Pubmed|11489886]

    • Structure

  • [PDB|1F7T] [Pubmed|10997907], [PDB|1F80] (complex with [protein|search|AcpA]) [Pubmed|10997907]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • [SW|Interactions]

  • [protein|search|AcpA]-[protein|search|AcpS] [Pubmed|10997907]

    • References

    Reviews

  • 15952903

    • Original Publications

  • 11489886,15955059,10997907,11867633