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acpS
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acpS

acyl-carrier protein synthase, 4-phosphopantetheine transferase
Locus
BSU_04620
Isoelectric point
9.91
Molecular weight
13.58 kDa
Protein length
121 aa Sequence Blast
Gene length
366 bp Sequence Blast
Function
fatty acid biosynthesis
Product
acyl-carrier protein synthase
Essential
yes
E.C.
2.7.8.7
Synonyms
ydcB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Lipid metabolism → Biosynthesis of lipids → Biosynthesis of fatty acids
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    515,710 516,075

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] --> adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein] (according to UniProt)

    • Protein family

  • P-Pant transferase superfamily (with Sfp/2, according to UniProt)

    • Cofactors

  • magnesium PubMed

    • Structure

  • 1F7T PubMed, 1F80 (complex with AcpA) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    acpS-ydcC
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-C103 (ydcB::erm), available at the NBRP B. subtilis, Japan
  • BKE04620 (acpS::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTATGATAACCTCCTTT, downstream forward: _UP4_TAGTCTGCATATTAGGGAAA

    • References

    Reviews

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    Original Publications

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