SubtiBank SubtiBank
nrdI
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nrdI

flavodoxin, ribonucleoside-diphosphate reductase
Locus
BSU_17370
Isoelectric point
8.58
Molecular weight
14.46 kDa
Protein length
130 aa Sequence Blast
Gene length
393 bp Sequence Blast
Function
synthesis of deoxyribonucleoside triphosphates
Product
ribonucleoside-diphosphate reductase
Essential
yes
Synonyms
ymaA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,868,617 1,869,009

Phenotypes of a mutant

  • essential PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • Provides oxidant (O2-) for assembly of dimanganic-tyrosyl radical (MnIII2-Y) cofactor in NrdF. PubMed
  • Protein family

  • nrdI family (with YosM, according to UniProt)
  • Paralogous protein(s)

    Cofactors

  • FMN PubMed
  • Structure

    Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • ResD: activation, PubMed, in ResD regulon
  • NrdR: repression, (predicted) PubMed, in NrdR regulon
  • PerR: transcription repression, PubMed, in PerR regulon
  • Regulation

  • expressed under anaerobic conditions (ResD) PubMed
  • Additional information

  • A ncRNA is predicted between 'ymzA' and 'nrdI' PubMed
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    References

    Reviews

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    Original Publications

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