yqcF [Sat Jan 28 2017 13:28:21 GMT+0100 (CET)]

antitoxin

locus: BSU25870

pI: 4.00

mw: 21.00 kDa

function: inhibition of the cytotoxic activity of YqcG

product: antitoxin

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.18|Toxins, antitoxins and immunity against toxins/ based on similarity]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|toxins, antitoxins and immunity against toxins], [SW|Skin element]

This gene is a member of the following [SW|regulons]

• [SW|Spo0A regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,662,712 -> 2,663,290

The protein

Catalyzed reaction/ biological activity

• part of a type II toxin/antitoxin system (with [SW|YqcG]) [Pubmed|27450630]

[SW|Interactions]

• [protein|search|YqcG]-[protein|search|YqcF] [Pubmed|22200572]

Expression and Regulation

Operon

• ''[protein|search|yqcG]-[protein|search|yqcF]'' [Pubmed|22383849]

Regulation

• expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
• induced by amino acid limitation [Pubmed|27450630]

Regulatory mechanism

• [SW|Spo0A]: transcription activation [Pubmed|14651647]

References

• 14651647,22200572,27450630