yvrB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

ABC transporter (ATP binding domain), similar to iron permease

locus: BSU33170

pI: 11.00

mw: 37.00 kDa

function: unknown

product: ABC transporter (ATP binding domain)

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.7|Uptake of cofactors]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.13|Biosynthesis/ acquisition of cobalamine (B12))]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|B12 riboswitch]

Gene

Coordinates on the chromosome (coding sequence): 3,402,469 -> 3,403,530

The protein

Structure

• [PDB|4R9U], the ''E. coli'' BtuC-BtuD complex, BtuC shares 40% identity, 71% similarity with YvrB, [Pubmed|25402482]

Expression and Regulation

Operon

• ''[SW|yvrC]-[SW|yvrB]-[SW|yvrA]-[SW|yvqK]'' [Pubmed|]

Regulation

• expression is decreased in the presence of cobalamin (vitamin B12) ([SW|B12 riboswitch]) [Pubmed|14704351]

Regulatory mechanism

• [SW|B12 riboswitch]: transcription termination upon binding of B12 [Pubmed|14704351]

References

• 10092453,25402482,14704351