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trxB [2019-04-18 10:24:24]
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trxB [2019-04-18 10:24:24]

thioredoxin reductase (NADPH)
Locus
BSU34790
Isoelectric point
4.99
Molecular weight
34.36 kDa
Protein length
316 aa Sequence Blast
Gene length
951 bp Sequence Blast
Function
keeps TrxA|thioredoxin in the reduced state
Product
thioredoxin reductase (NADPH)
Essential
yes
E.C.
1.8.1.9
Synonyms
yvcH
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Electron transport and ATP synthesis → Electron transport/ other
  • Lifestyles → Coping with stress → Resistance against oxidative and electrophile stress
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    3,573,207 3,574,157

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • Thioredoxin NADP = thioredoxin disulfide NADPH (according to Swiss-Prot)

    • Protein family

  • class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)

    • Cofactors

  • FMN or FAD PubMed

    • Structure

  • 4GCM (from S. aureus, 71% identity)

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    trxB
    Description
    PubMed

    Regulatory mechanism

  • Spx: activation, PubMed, in Spx regulon

    • Regulation

  • induced by cell wall stress (Spx) PubMed
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    References

    Reviews

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    Original publications

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