trxB [Fri Feb 26 2016 17:41:24 GMT+0100 (CET)]

thioredoxin reductase (NADPH)

Locus: BSU34790

Isoelectric point: 4.00

Molecular weight: 34.00 kDa

Function: keeps TrxA|thioredoxin in the reduced state

Product: thioredoxin reductase (NADPH)

Essential: yes

E.C.: 1.8.1.9

Synonyms: yvcH

Genomic Context

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Categories containing this gene/protein

• Metabolism → Electron transport and ATP synthesis → Electron transport/ other
• Lifestyles → Coping with stress → Resistance against oxidative and electrophile stress
• Groups of genes → Essential genes

Categories containing this gene/protein

• electron transport/ other, resistance against oxidative and electrophile stress, essential genes

This gene is a member of the following regulons

• Spx regulon

Gene

Coordinates on the chromosome (coding sequence): 3,573,207 -> 3,574,157

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• Thioredoxin NADP = thioredoxin disulfide NADPH (according to Swiss-Prot)

Protein family

• class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)

Cofactors

• FMN or FAD PubMed

Structure

• 4GCM (from S. aureus, 71% identity)

Localization

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Regulatory mechanism

• Spx: transcription activation PubMed

Additional information

• A ncRNA is predicted between 'yvcI' and 'trxB' PubMed

References

Reviews

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Original publications

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