cmk [Mon Aug 31 2015 13:55:19 GMT+0200 (CEST)]

cytidylate kinase (CMP, dCMP)

locus: BSU22890

pI: 5.00

mw: 24.00 kDa

function: synthesis of CTP and dCTP

product: cytidylate kinase (CMP, dCMP)

essential: yes

ec: 2.7.4.14

synonyms: jofC, ypfC

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

syns: jofC, ypfC

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of nucleotides], [SW|essential genes]

Gene

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• ATP + (d)CMP = ADP + (d)CDP (according to Swiss-Prot)

Protein family

• Type 1 subfamily (according to Swiss-Prot)

Structure

• [PDB|1CKE] (from ''Escherichia coli'', 38% identity, 54% similarity) [Pubmed|9862805]

References

• 9126287