SubtiBank SubtiBank
glsA [2017-8-11 16:0:3]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

glsA [2017-8-11 16:0:3]

glutaminase, low affinity for glutamine
locus
BSU02430
pI
5.32
mw
36.03 kDa
protein length
327 aa Sequence Blast
gene length
981 bp Sequence Blast
function
glutamine degradation
product
glutaminase
essential
no
ec
3.5.1.2
synonyms
ybgJ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate]

    • Gene

    Coordinates
    264,191 → 265,174

    The protein

    Catalyzed reaction/ biological activity

  • l-glutamine + H2O = L-glutamate + NH3 (according to Swiss-Prot)

    • Protein family

  • glutaminase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|F31DD310F0D80ECC7C6D1E5DDB8EAF32565A3D51|YlaM]

    • Structure

  • [PDB|3BRM] [PDB|1MKI][Pubmed|18459799]

    • Expression and Regulation

    Operons

    genes
    [gene|1A415DC85354373EA4866733C3AE43F510BD3C56|glsA]-[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]
    description
    [Pubmed|15995196]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|15995196], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|GlnL]: activation, [Pubmed|15995196], in [regulon|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|GlnL regulon]

    • regulation

  • induced in the presence of glutamine ([protein|search|GlnL]) [Pubmed|15995196]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B943 (ybgJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1942 NBRP B. subtilis, Japan]

    • References

  • 15995196,18459799