moaA [2019-08-12 10:02:54]

molybdopterin precursor biosynthesis

Locus: BSU_36700

Isoelectric point: 9.28

Molecular weight: 38.39 kDa

Protein length: 341 aa

Gene length: 1026 bp

Function: nitrate respiration

Product: unknown

Essential: no

Synonyms: narA,narAB

Genomic Context

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Categories containing this gene/protein

• Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of molybdopterin

Gene

Coordinates: 3,772,325 3,773,350

The protein

Catalyzed reaction/ biological activity

• involved in the first step of molybdenum cofactor biosynthesis (together with YdiG)

Protein family

• Radical SAM superfamily (according to UniProt)

Cofactors

• Fe-S cluster PubMed
• S-adenosyl methionine (according to UniProt)

Structure

• 1TV7 (from Staphylococcus aureus, 49% identity) PubMed

Expression and Regulation

Operons

• Genes: fdhD-moaA
  Description: PubMed

Biological materials

Mutant

• BKE36700 (moaA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT
• BKK36700 (moaA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT

References

Reviews

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Original publications

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