queC [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

synthesis of the modified ribonucleotide queuosine

locus: BSU13720

pI: 5.00

mw: 24.00 kDa

function: tRNA modification

product: unknown

essential: no

synonyms: ykvJ

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]

[SW|Categories] containing this gene/protein

• [SW|translation]

This gene is a member of the following [SW|regulons]

• [SW|preQ1 riboswitch]

Gene

Coordinates on the chromosome (coding sequence): 1,439,448 -> 1,440,107

The protein

Protein family

• queC family (according to Swiss-Prot)

Structure

• [PDB|3BL5] [Pubmed|18491386]

Expression and Regulation

Operon

• ''[protein|search|queC]-[protein|search|queD]-[protein|search|queE]-[protein|search|queF]'' [Pubmed|14660578]

Regulation

• repressed in the presence of queuosine ([SW|preQ1 riboswitch]) [Pubmed|19285444]

Regulatory mechanism

• [SW|preQ1 riboswitch]: transcriptional antitermination in the absence of queuosine [Pubmed|19285444]

References

• 18491386,14660578,17384645,19285444,19354300,24003028,21410253,21375305,24663240