transcriptional regulator (repressor or activator) of a subset of sigma-K-dependent late spore coat genes
function
regulation of SigK-dependent gene expression
product
transcriptional regulator (LuxR-FixJ family)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.2|Additional germination proteins][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|germination]This gene is a member of the following [SW|regulons]
[SW|CitB regulon], [SW|SigK regulon], , [SW|SpoIIID regulon]Gene
Phenotypes of a mutant
unable to germinate efficiently [Pubmed|3139490]The protein
Protein family
LuxR-FixJ family of transcription regulatorsStructure
[PDB|1FSE]Expression and Regulation
Operon
''gerE'' [Pubmed|3114423][SW|Sigma factor]
[protein|search|SigK] [Pubmed|15699190]Regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [SW|SpoIIID]) [Pubmed|15699190,7896717]expression is subject to variation between individual cells [Pubmed|26279233]Regulatory mechanism
[SW|SpoIIID]: transcription activation [Pubmed|7896717][SW|CitB]: binding of the mRNA, results in mRNA accumulation [Pubmed|16923907]Labs working on this gene/protein
[SW|Arthur Aronson], Purdue University, West Lafayette, USA [http://wwwdev.gradschool.purdue.edu/PULSe/faculty.cfm?fid=5&range=0 homepage][SW|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]References
7519271,2474075,11418558,10400595,7592393,11741866,7592342,3135411,9852018,1691789,15383836,11150673,1518043,7814326,14523132,12031481,11418558,3114423,7896717,11243786,17890309,15470121,20435725,21670523,23064347,3139490,25259857,6787012,26279233,16923907 
