SubtiBank SubtiBank
parE [Tue Sep 06 2016 17:15:10 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

parE [Tue Sep 06 2016 17:15:10 GMT+0200 (CEST)]

subunit of DNA topoisomerase IV
Locus
BSU18090
Isoelectric point
6.00
Molecular weight
72.00 kDa
Function
chromosome segregation and compaction
Product
subunit of DNA topoisomerase IV
Essential
yes
E.C.
5.99.1.-
Synonyms
grlB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Information processing → Genetics → DNA condensation/ segregation
  • Groups of genes → Essential genes

    • Categories containing this gene/protein

  • DNA condensation/ segregation, essential genes

    • This gene is a member of the following regulons

  • LexA regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,933,477 -> 1,935,444

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Protein family

  • type II topoisomerase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • GyrB

    • Structure

  • 4I3H (from Streptococcus pneumoniae, 70% identity) PubMed

    • Localization

  • Nucleoid (Homogeneous) PubMed
  • uniformly distributed throughout the cell PubMed

    • Interactions

  • ParC-ParE PubMed

    • Expression and Regulation

    Operon

  • parE-parC PubMed

    • Regulation

  • induced by DNA damage (LexA) PubMed

    • Regulatory mechanism

  • LexA: transcription repression PubMed

    • Additional information

  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of parE PubMed

    • References

    Loading