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yxnA [2018-07-26 12:27:18]
general stress protein, similar to glucose 1-dehydrogenase, survival of ethanol stress
function
survival of ethanol stress
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
4,108,058 → 4,109,128
The protein
Paralogous protein(s)
[protein|0927C7D45721F47F5ED2646CAAC324A308FD7724|YqjQ]: Structure
[PDB|4NBU] ([protein|439B468A13137000FB42E9389391CB4986FFED84|FabG] from Bacillus sp., corresponds to aa 26 ... 255 of YxnA, 32% identity) [pubmed|24212572]Expression and Regulation
Operons
genes
[gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]
description
[Pubmed|10746760]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]view in new tabBiological materials
Mutant
MGNA-B762 (yxnA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1761 NBRP B. subtilis, Japan]BKE40000 (Δ[gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAGAGATCCCTCCTAG, downstream forward: _UP4_TAATCTCTGACCATAAGAAABKK40000 (Δ[gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAGAGATCCCTCCTAG, downstream forward: _UP4_TAATCTCTGACCATAAGAAAReferences
15805528,10746760,24212572