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ktrC [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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ktrC [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

low affinity potassium transporter KtrC-KtrD, peripheric membrane component
Locus
BSU14510
Isoelectric point
5.00
Molecular weight
24.00 kDa
Function
potassium uptake
Product
low affinity potassium transporter KtrC-KtrD,
peripheric membrane component (proton symport)
Essential
no
Synonyms
ylxV, yzaC, ykqB

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

Gene

Coordinates on the chromosome (coding sequence)
1,520,531 -> 1,521,196

The protein

Paralogous protein(s)

Domains

  • contains a RCK_N domain at the N-terminus (according to [http://www.uniprot.org/uniprot/?query=domain:RCK N-terminal domain* UniProt])
  • contains a c-di-AMP-binding RCK_C domain at the C-terminus (according to [http://www.uniprot.org/uniprot/?query=domain:RCK C-terminal domain* UniProt]) PubMed
  • Effectors of protein activity

  • the protein binds c-di-AMP PubMed
  • Structure

  • 4J7C (the KtrA-KtrB complex, 56% identity) PubMed
  • 4XTT (the S. aureus KtrA RCK_C domain in complex with c-di-AMP, 57% identity) PubMed
  • Localization

  • peripheral membrane protein PubMed
  • Interactions

    Expression and Regulation

    Operon

  • ktrC PubMed
  • Regulation

  • constitutively expressed PubMed
  • Biological materials

    Mutant

  • GHB6 (ktrC::spec), PubMed (available in Erhard Bremer's and Jörg Stülke's) labs, available at BGSC as 1A955
  • GP2079 (ktrC::tet), available in Jörg Stülke's lab
  • GP2083 (D(ktrA-ktrB)::aphA3 DktrC::tet), available in Jörg Stülke's lab
  • Expression vector

  • pGP2907 (N-terminal His-tag, purification from E. coli, in pWH844), available in Jörg Stülke's lab
  • Labs working on this gene/protein

  • Erhard Bremer, University of Marburg, Germany homepage
  • References

    Reviews

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    Original publications

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