asnO [Tue Apr 12 2016 20:25:32 GMT+0200 (CEST)]

asparagine synthase (glutamine-hydrolysing)

locus: BSU10790

pI: 5.00

mw: 70.00 kDa

function: biosynthesis of asparagine

product: asparagine synthase (glutamine-hydrolysing)

essential: no

ec: 6.3.5.4

synonyms: yisO, yucB

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.5|Biosynthesis/ acquisition of aspartate/ asparagine]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigE regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,157,237 -> 1,159,081

The protein

Catalyzed reaction/ biological activity

• ATP L-aspartate L-glutamine H₂O = AMP diphosphate L-asparagine L-glutamate (according to Swiss-Prot)

Protein family

• glutamine amidotransferase type-2 domain (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|asnO]'' [Pubmed|10498721]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|10498721]

Regulation

• expressed during sporulation ([protein|search|SigE]) [Pubmed|10498721]
• subject to positive regulation by [SW|SpoIIID] [Pubmed|15383836]

References

Reviews

• 12859215,11395405

Original publications

• 10498721,15383836