yrkP [2017-12-15 18:23:40]

two-component response regulator (OmpR family)

locus: BSU26430

pI: 5.69

mw: 26.65 kDa

protein length: 231 aa

gene length: 693 bp

function: unknown

product: two-component response regulator (OmpR family)

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]

Gene

Coordinates: 2,704,435 → 2,705,130

The protein

Protein family

• [SW|OmpR family] of two-component response regulators

Modification

• phosphorylated by [protein|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|YrkQ] on an Asp residue

Effectors of protein activity

• phosphorylation likely affects DNA-binding activity

Expression and Regulation

Operons

• genes: [gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]-[gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]-[gene|E0DF6DE230AD0B632EEC0A1FB11EB32E59BD573E|yrkR]
  description: [Pubmed|18175906]

  regulatory mechanism

  • [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP]: activation, [Pubmed|18175906], in [regulon|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP regulon]

Biological materials

Mutant

• BKE26430 (Δ[gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE26430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCTCTCTCACCTCATG, downstream forward: _UP4_CGATTTGGCGCATCTTAAAT
• BKK26430 (Δ[gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK26430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCTCTCTCACCTCATG, downstream forward: _UP4_CGATTTGGCGCATCTTAAAT

References

• 10094672,18175906,23504016