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fbpB [2017-11-16 15:34:48]
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fbpB [2017-11-16 15:34:48]

Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation
locus
BSU04530
pI
10.73
mw
6.88 kDa
protein length
59 aa Sequence Blast
gene length
177 bp Sequence Blast
function
RNA chaperone
product
Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation
essential
no
synonyms
ydbN
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other]
  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.2|RNA chaperones]
  • [category|SW 6|Groups of genes] → [category|SW 6.8|Short peptides]

    • Gene

    Coordinates
    506,322 → 506,501

    Phenotypes of a mutant

  • transcription profile of a ''[gene|35ABF185A1AD60E21ECF32AF9D01123307B5152D|fbpA] [gene|147AFEBEA546FDBEEB08E9A8D9C7BCDC9B83CC90|fbpB]'' double mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] [Pubmed|22389480]

    • Expression and Regulation

    Operons

    genes
    [gene|35ABF185A1AD60E21ECF32AF9D01123307B5152D|fbpA]-[gene|147AFEBEA546FDBEEB08E9A8D9C7BCDC9B83CC90|fbpB]
    description
    [pubmed|18697947]

    regulatory mechanism

  • [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]: repression, [pubmed|12354229], in [regulon|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur regulon]

    • regulation

  • induced by iron starvation (third wave, under extreme starvation, iron sparing response) ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]) [pubmed|29133393,12354229]
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    Biological materials

    Mutant

  • BKE04530 (Δ[gene|147AFEBEA546FDBEEB08E9A8D9C7BCDC9B83CC90|fbpB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTCTAACTCCGTCAGC, downstream forward: _UP4_TAAAAAGAGCCGGTAAGGCT
  • BKK04530 (Δ[gene|147AFEBEA546FDBEEB08E9A8D9C7BCDC9B83CC90|fbpB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTCTAACTCCGTCAGC, downstream forward: _UP4_TAAAAAGAGCCGGTAAGGCT

    • References

  • 12354229,18697947,20525796,22389480,22427629