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recX [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
recombination protein, modulates the SOS response and facilitates RecA-mediated recombinational repair and genetic recombination
function
DNA repair/ recombination
product
recombination protein
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins][SW|Categories] containing this gene/protein
[SW|DNA repair/ recombination]Gene
Coordinates on the chromosome (coding sequence)
925,633 -> 926,427
Phenotypes of a mutant
reduced natural tranformation with plasmid or chromosomal DNA [Pubmed|23284295]drastically reduced survival of mature dormant spores after exposure to ultrahigh vacuum desiccation and ionizing radiation that induce single strand (ss) DNA nicks and double-strand breaks (DSBs) [Pubmed|24285298]The protein
Catalyzed reaction/ biological activity
modulates the "length or packing" of a [protein|search|RecA] filament, thereby [protein|search|RecX] facilitates the initiation of recombination and increases recombination across species [Pubmed|23284295]Protein family
recX family (according to Swiss-Prot)[SW|Localization]
forms foci on the nucleoid upon DNA damage [Pubmed|23284295]forms foci at the cells poles and/ or the nucleoid upon induction of genetic competence [Pubmed|23284295]Expression and Regulation
Operon
''[protein|search|recX]-[protein|search|yfhH]'' [Pubmed|22383849]References
23284295,22383849,24285298,24285298