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recX [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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recX [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

recombination protein, modulates the SOS response and facilitates RecA-mediated recombinational repair and genetic recombination
locus
BSU08520
pI
6.29
mw
30.00 kDa
function
DNA repair/ recombination
product
recombination protein
essential
no
synonyms
yfhG

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination]
  • Gene

    Coordinates on the chromosome (coding sequence)
    925,633 -> 926,427

    Phenotypes of a mutant

  • reduced natural tranformation with plasmid or chromosomal DNA [Pubmed|23284295]
  • drastically reduced survival of mature dormant spores after exposure to ultrahigh vacuum desiccation and ionizing radiation that induce single strand (ss) DNA nicks and double-strand breaks (DSBs) [Pubmed|24285298]
  • The protein

    Catalyzed reaction/ biological activity

  • modulates the "length or packing" of a [protein|search|RecA] filament, thereby [protein|search|RecX] facilitates the initiation of recombination and increases recombination across species [Pubmed|23284295]
  • Protein family

  • recX family (according to Swiss-Prot)
  • [SW|Localization]

  • forms foci on the nucleoid upon DNA damage [Pubmed|23284295]
  • forms foci at the cells poles and/ or the nucleoid upon induction of genetic competence [Pubmed|23284295]
  • Expression and Regulation

    Operon

  • ''[protein|search|recX]-[protein|search|yfhH]'' [Pubmed|22383849]
  • References

  • 23284295,22383849,24285298,24285298