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ywcE [2019-06-12 10:29:16]
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ywcE [2019-06-12 10:29:16]

holin, required for spore morphogenesis and germination
Locus
BSU38130
Isoelectric point
9.85
Molecular weight
9.82 kDa
Protein length
87 aa Sequence Blast
Gene length
264 bp Sequence Blast
Function
required for spore morphogenesis and germination
Product
holin
Essential
no
Synonyms
ipa-41r
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Sporulation → Sporulation/ other
  • Lifestyles → Sporulation → Germination → Additional germination proteins
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    3,914,009 3,914,272

    Phenotypes of a mutant

  • forms spores with a reduced outer coat PubMed

    • The protein

    Protein family

  • ywcE family (according to Swiss-Prot)

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    ywcE
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • ResD: repression, PubMed, in ResD regulon

    • Regulation

  • repressed during the log phase (AbrB), expressed only at the onset of stationary phase PubMed
  • repressed under anaerobic conditions (ResD) PubMed
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    Biological materials

    Mutant

  • BKE38130 (ywcE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACCCGTCTCCTTTCATT, downstream forward: _UP4_TGAAGACAGCAAAAAACCCT
  • BKK38130 (ywcE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACCCGTCTCCTTTCATT, downstream forward: _UP4_TGAAGACAGCAAAAAACCCT

    • Labs working on this gene/protein

  • Charles Moran, Emory University, NC, USA homepage

    • References

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