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pcp
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pcp

pyrrolidone-carboxylate peptidase
Locus
BSU_02650
Isoelectric point
6.42
Molecular weight
23.63 kDa
Protein length
215 aa Sequence Blast
Gene length
648 bp Sequence Blast
Function
removal of the N-terminal pyroglutamyl group from peptides
Product
pyrrolidone-carboxylate peptidase
Essential
no
E.C.
3.4.11.8
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein modification/ other

    • Gene

    Coordinates
    286,773 287,420

    The protein

    Catalyzed reaction/ biological activity

  • Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro (according to UniProt)

    • Protein family

  • peptidase C15 family (single member, according to UniProt)

    • Structure

  • 1AUG (from B. amyloliquefaciens, 72% identity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    pcp
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE02650 (pcp::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTCCCATCTCCTTTTT, downstream forward: _UP4_CACTAAGCGGCCGCCGCTGT
  • BKK02650 (pcp::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTCCCATCTCCTTTTT, downstream forward: _UP4_CACTAAGCGGCCGCCGCTGT

    • References

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