two-component response regulator, regulation of citrate uptake
function
regulation of citrate uptake
product
two-component response regulator
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|transcription factors and their control], [SW|phosphoproteins]Gene
Coordinates on the chromosome (coding sequence)
832,545 -> 833,225
Phenotypes of a mutant
no growth with citrate as sole carbon source [Pubmed|10972810]The protein
Catalyzed reaction/ biological activity
binding to the promoter of the ''[protein|search|citM]-[protein|search|yflN]'' operon and activation of transcription in the presence of citrate [Pubmed|10972810]Modification
phosphorylated by [protein|search|CitS] on an Asp residueEffectors of protein activity
phosphorylation likely affects DNA-binding activity[SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|CitS]-[protein|search|CitT]Expression and Regulation
Operon
''[protein|search|citS]-[protein|search|citT]-[protein|search|yflP]'' [Pubmed|10972810]References
10094672,16842348,10972810 
