yidC2 [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

Sec-independent membrane protein translocase, required for development of genetic competence

Locus: BSU23890

Isoelectric point: 9.00

Molecular weight: 30.00 kDa

Function: membrane insertion of proteins and protein secretion

Product: Sec-independent membrane protein translocase

Essential: no

Synonyms: yqjG, oxaAB

Genomic Context

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Categories containing this gene/protein

• Information processing → Genetics → Genetic competence
• Information processing → Protein synthesis, modification and degradation → Protein secretion
• Lifestyles → Exponential and early post-exponential lifestyles → Genetic competence
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• protein secretion, genetic competence, membrane proteins

This gene is a member of the following regulons

• MifM regulon

Gene

Coordinates on the chromosome (coding sequence): 2,483,904 -> 2,484,731

The protein

Protein family

• YidC/Oxa1/Alb3 family PubMed

Paralogous protein(s)

• SpoIIIJ, one of the two proteins has to be present for viability PubMed

Structure

• 3WO6 (from Bacillus halodurans, 41% identity) PubMed

Localization

• membrane PubMed

Expression and Regulation

Operon

• mifM-yidC2 PubMed

Regulation

• repressed by large amounts of SpoIIIJ, induced by small amounts of SpoIIIJ (MifM) PubMed

Regulatory mechanism

• MifM: attenuation mechanism, an mRNA hairpin of the yqjG transcript unfold upon translation arrest of MifM at decreased SpoIIIJ levels PubMed

References

Reviews

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Original publications

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