dps

iron storage protein, general stress protein, resistance against ethanol and paraquat stresses stress and survival at low temperatures

Locus: BSU_30650

Isoelectric point: 4.44

Molecular weight: 16.45 kDa

Protein length: 145 aa

Gene length: 438 bp

Function: iron storage, survival of of stress conditions

Product: mini-ferritin

Essential: no

Synonyms: ytkB

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Homeostasis → Acquisition of iron → Acquisition of iron / Other
• Metabolism → Additional metabolic pathways → Iron metabolism → Acquisition of iron / Other
• Lifestyles → Coping with stress → General stress proteins (controlled by SigB)
• Lifestyles → Coping with stress → Resistance against oxidative and electrophile stress

Gene

Coordinates: 3,136,238 3,136,675

The protein

Protein family

• dps family (with MrgA, according to UniProt)

Paralogous protein(s)

• MrgA

Structure

• 1JIG (from B. anthracis, 63% identity) PubMed

Expression and Regulation

Operons

• Genes: dps
  Description: PubMed

  Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon

  Regulation

  • induced by stress (SigB) PubMed

• Genes: ytkA-dps
  Description: PubMed

Biological materials

Mutant

• MGNA-A296 (ytkB/dps::erm), available at the NBRP B. subtilis, Japan
• BKE30650 (dps::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGTATCTCCTCCTTGTT, downstream forward: _UP4_TAAGTTCAAAAATAGAACGG
• BKK30650 (dps::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGTATCTCCTCCTTGTT, downstream forward: _UP4_TAAGTTCAAAAATAGAACGG

References

Reviews

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Original publications

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