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patB [Mon Aug 31 2015 13:56:31 GMT+0200 (CEST)]
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patB [Mon Aug 31 2015 13:56:31 GMT+0200 (CEST)]

cystathione-beta-lyase
locus
BSU31440
pI
5.44
mw
42.00 kDa
function
biosynthesis of methionine
product
cystathione-beta-lyase
essential
no
ec
4.4.1.8
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.10|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of amino acids]
  • The protein

    Catalyzed reaction/ biological activity

  • L-cystathionine + H2O = L-homocysteine + NH3 + pyruvate (according to Swiss-Prot)
  • Protein family

  • MalY/patB cystathionine beta-lyase subfamily (according to Swiss-Prot)
  • Structure

  • [PDB|3T32] (from ''B. anthracis'', 46% identity, 75% similarity)
  • Expression and Regulation

    Operon

  • ''[protein|search|patB]'' [Pubmed|9274030]
  • Biological materials

    Mutant

  • 1A952 ( ''patB''::''cat''), [Pubmed|15760717], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A952&Search=1A952 BGSC]
  • References

  • 9274030,15760717