SubtiBank SubtiBank
patB
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patB

cystathione-beta-lyase
Locus
BSU_31440
Isoelectric point
5.44
Molecular weight
42.63 kDa
Protein length
387 aa Sequence Blast
Gene length
1164 bp Sequence Blast
Function
biosynthesis of methionine
Product
cystathione-beta-lyase
Essential
no
E.C.
4.4.1.8
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of methionine/ S-adenosylmethionine

    • Gene

    Coordinates
    3,228,778 3,229,941

    The protein

    Catalyzed reaction/ biological activity

  • H2O + L,L-cystathionine --> L-homocysteine + NH4+ + pyruvate (according to UniProt)

    • Protein family

  • class-II pyridoxal-phosphate-dependent aminotransferase family (according to UniProt)

    • Cofactors

  • PLP (according to UniProt)

    • Structure

  • 3T32 (from B. anthracis, 46% identity, 75% similarity)

    • Expression and Regulation

    Operons

    Genes
    patB
    Description
    PubMed
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    Biological materials

    Mutant

  • 1A952 ( patB::cat), PubMed, available at BGSC
  • BKE31440 (patB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTGTTACCCCCTCATG, downstream forward: _UP4_TAAATATAGCTGTAAACGCC
  • BKK31440 (patB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTGTTACCCCCTCATG, downstream forward: _UP4_TAAATATAGCTGTAAACGCC

    • References

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