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lytH [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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lytH [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

differentiation-associated peptidoglycan hydrolase involved in endospore cortex maturation
locus
BSU32340
pI
6.00
mw
39.00 kDa
function
endospore cortex maturation
product
peptidoglycan hydrolase
essential
no
synonyms
yunA, yutA

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.4|Endopeptidases]
  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall degradation/ turnover], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,321,455 -> 3,322,435

    The protein

    Catalyzed reaction/ biological activity

  • cleaves the peptide bond between L-Ala (position 1 in the peptioglycan peptide) and D-Glu (position 2) [Pubmed|18266855]
  • Protein family

  • peptidase M23B family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''lytH'' [Pubmed|12813075]
  • [SW|Sigma factor]

  • [protein|search|SigK] [Pubmed|12813075]
  • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|12813075]
  • References

    Reviews

  • 18266855
  • Original publications

  • 12813075