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SR4 [Mon Jan 25 2016 11:10:11 GMT+0100 (CET)]
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SR4 [Mon Jan 25 2016 11:10:11 GMT+0100 (CET)]

antitoxin RNA, inhibits bsrG translation and causes destabilization of the bsrG mRNA
locus
new_2273724_2273988_c
pI
0.00
mw
0.00 kDa
function
protection of the cell
product
antitoxin RNA
synonyms
SR4,S810
Outlinks
KEGGBsubCyc

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.1|Type 1 TA systems]
  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.5|Regulatory RNAs]

    • [SW|Categories] containing this gene/protein

  • [SW|toxins, antitoxins and immunity against toxins], [SW|SP-beta prophage], [SW|ncRNA]

    • Gene

    Coordinates on the chromosome
    2,273,724 -> 2,273,988

    Phenotypes of a mutant

  • cell lysis on agar plates [Pubmed|22229825]

    • Protein

    Catalyzed reaction/ biological activity

  • binds the ''[protein|search|bsrG]'' mRNA and triggers its degradation [Pubmed|22229825], moreover SR4 inhibits ''[protein|search|bsrG]'' [SW|translation] [Pubmed|23969414]

    • Expression and Regulation

    Operon

  • ''[SW|SR4]'' [Pubmed|22229825]

    • Sigma factor

  • [SW|SigA] [Pubmed|22229825]

    • Additional information

  • half-life of the RNA: 3 min [Pubmed|22229825]
  • maturation of the RNA requires [protein|search|PnpA] [Pubmed|22229825]

    • Labs working on this gene/protein

  • [SW|Sabine Brantl], Jena, Germany

    • References

  • 18948176,20525796,23969414,22229825,26234942