secE [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

preprotein translocase subunit

locus: BSU01000

pI: 10.00

mw: 6.00 kDa

function: protein secretion

product: preprotein translocase subunit

essential: yes

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|protein secretion], [SW|essential genes], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 117,532 -> 117,711

Phenotypes of a mutant

• essential [Pubmed|12682299] [Pubmed|7968510]

The protein

Protein family

• secE/SEC61-gamma family (according to Swiss-Prot)

[SW|Domains]

• transmembrane protein with a single TM domain

Structure

• [PDB|3DL8] (structure of the ([protein|search|SecY]-[protein|search|SecE]-[protein|search|SecG])-[protein|search|SecA] complex) [Pubmed|18923516]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

[SW|Interactions]

• ([protein|search|SecY]-[protein|search|SecE]-[protein|search|SecG])2-[protein|search|SecA]2 [Pubmed|18923516]

Additional information

• B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.

References

Reviews

• 25212246

Original publications

• 7968510,18923516