N-acetylglutamate synthase
function
biosynthesis of arginine
product
N-acetylglutamate synthase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine][SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of amino acids]This gene is a member of the following [SW|regulons]
[SW|AhrC regulon], [SW|CodY regulon]Gene
Coordinates on the chromosome (coding sequence)
1,196,091 -> 1,197,311
The protein
Catalyzed reaction/ biological activity
N(2)-acetyl-L-ornithine L-glutamate = L-ornithine N-acetyl-L-glutamate (according to Swiss-Prot) Protein family
argJ family (according to Swiss-Prot)Structure
[PDB|1VZ6] (from ''Streptomyces clavuligerus'', 36% identity)[SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|argC]-[protein|search|argJ]-[protein|search|argB]-[protein|search|argD]-[protein|search|carA]-[protein|search|carB]-[protein|search|argF]'' [Pubmed|7511775][SW|Sigma factor]
[protein|search|SigA] [Pubmed|7511775]Regulation
repressed by casamino acids ([protein|search|CodY]) [Pubmed|12107147]repressed by arginine ([protein|search|AhrC]) [Pubmed|1312212]Regulatory mechanism
[protein|search|AhrC]: transcription repression [Pubmed|1312212][protein|search|CodY]: transcription repression [Pubmed|24843172]References
19649769,6096675,12107147,24843172 
