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cdd
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cdd

cytidine deaminase
Locus
BSU_25300
Isoelectric point
4.70
Molecular weight
14.71 kDa
Protein length
136 aa Sequence Blast
Gene length
411 bp Sequence Blast
Function
pyrimidine interconversion
Product
cytidine deaminase
Essential
no
E.C.
3.5.4.5
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,610,927 2,611,337

The protein

Catalyzed reaction/ biological activity

  • cytidine + H+ + H2O --> NH4+ + uridine (according to UniProt)
  • 2'-deoxycytidine + H+ + H2O --> 2'-deoxyuridine + NH4+ (according to UniProt)
  • Protein family

    Domains

  • CMP/dCMP-type deaminase domain (aa 1–128) (according to UniProt)
  • Cofactors

  • Zn2+ PubMed
  • Structure

  • 1JTK (complex with inhibitor) PubMed
  • 1UWZ (with Arg56Ala substitution) PubMed
  • 1UX0 (with Arg56Gln substitution) PubMed
  • 1UX1 (with Cys53His and Arg56Gln substitutions) PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigB: sigma factor, PubMed, in SigB regulon
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    Biological materials

    Mutant

  • BKE25300 (cdd::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTGTACATTCCTCTCTT, downstream forward: _UP4_GGCGCATTTTCATCGGAGGA
  • BKK25300 (cdd::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTGTACATTCCTCTCTT, downstream forward: _UP4_GGCGCATTTTCATCGGAGGA
  • References

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