rpsL

ribosomal protein

Locus: BSU_01100

Isoelectric point: 11.00

Molecular weight: 15.00 kDa

Protein length: 138 aa

Gene length: 417 bp

Function: translation

Product: ribosomal protein S12 (BS12)

Essential: yes

Synonyms: strA,fun

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Ribosomal proteins
• Groups of genes → Essential genes
• Groups of genes → Phosphoproteins → Phosphorylation on an Arg residue

Gene

Coordinates: 129,702 130,118

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• Universal ribosomal protein uS12 family (single member, according to UniProt)

Modification

• phosphorylated on Arg-123 PubMed

Structure

• 3J9W (the ribosome) PubMed

Localization

• ribosome (according to UniProt)

Expression and Regulation

Operons

• Genes: rplGB-rpsL-rpsG-fusA-tufA
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed
  • the mRNA is processed between rplGB and rpsL by RNase Y, this requires the YmcA-YlbF-YaaT complex PubMed

References

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