similar to NAD(P)H dehydrogenase (quinone)
function
resistance to 2-methylhydroquinone
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][SW|Categories] containing this gene/protein
[SW|sporulation proteins], [SW|resistance against oxidative and electrophile stress]This gene is a member of the following [SW|regulons]
[SW|MhqR regulon], [SW|SigG regulon]Gene
Coordinates on the chromosome (coding sequence)
3,445,442 -> 3,446,077
The protein
Protein family
azoreductase type 1 family (according to Swiss-Prot)Paralogous protein(s)
[SW|AzoR1]Structure
[PDB|3P0R] (from B. anthracis, 43% identity, 61% similarity)Expression and Regulation
Operon
''azoR2'' [Pubmed|17725564][SW|Sigma factor]
[protein|search|SigA] [Pubmed|17725564], [protein|search|SigG] [Pubmed|16497325]Regulation
induced by catechol and 2-methylhydroquinone (2-MHQ) ([protein|search|MhqR]) [Pubmed|17725564]repressed by casamino acids [Pubmed|12107147]Regulatory mechanism
[protein|search|MhqR]: transcription repression [Pubmed|17725564]Biological materials
Mutant
MGNA-A444 (yvaB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/444 NBRP B. subtilis, Japan]References
17725564,18208493,16497325,12107147