SubtiBank SubtiBank
azoR2 [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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azoR2 [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

similar to NAD(P)H dehydrogenase (quinone)
locus
BSU33540
pI
5.00
mw
23.00 kDa
function
resistance to 2-methylhydroquinone
product
azoreductase
essential
no
synonyms
yvaB

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins], [SW|resistance against oxidative and electrophile stress]
  • This gene is a member of the following [SW|regulons]

  • [SW|MhqR regulon], [SW|SigG regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,445,442 -> 3,446,077

    The protein

    Protein family

  • azoreductase type 1 family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [SW|AzoR1]
  • Structure

  • [PDB|3P0R] (from B. anthracis, 43% identity, 61% similarity)
  • Expression and Regulation

    Operon

  • ''azoR2'' [Pubmed|17725564]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17725564], [protein|search|SigG] [Pubmed|16497325]
  • Regulation

  • induced by catechol and 2-methylhydroquinone (2-MHQ) ([protein|search|MhqR]) [Pubmed|17725564]
  • repressed by casamino acids [Pubmed|12107147]
  • Regulatory mechanism

  • [protein|search|MhqR]: transcription repression [Pubmed|17725564]
  • Biological materials

    Mutant

  • MGNA-A444 (yvaB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/444 NBRP B. subtilis, Japan]
  • References

  • 17725564,18208493,16497325,12107147