gerR [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

probably DNA-binding protein, regulates transcription of some spore coat genes

locus: BSU15090

pI: 7.11

mw: 22.00 kDa

function: spore coat formation and resistance of spores to lysozyme

product: unknown

essential: no

synonyms: ylbO

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.8|Not yet assigned]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigE regulon], [SW|SpoIIID regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,576,129 -> 1,576,710

The protein

Modification

• phosphorylated on Ser-180 [Pubmed|20509597]

Expression and Regulation

Operon

• ''gerR'' (according to [http://dbtbs.hgc.jp/COG/prom/gerR.html DBTBS])

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|15699190]

Regulation

• expressed during sporulation in the mother cell ([protein|search|SigE], [SW|SpoIIID]) [Pubmed|15699190,20435725]
• repressed by glucose (3.2-fold) [Pubmed|12850135]
• repressed by casamino acids [Pubmed|12107147]

Regulatory mechanism

• [SW|SpoIIID]: transcription activation [Pubmed|20435725]

References

• 15383836,15621419,20435725,12850135,12107147,20509597