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trpS [2018-05-30 14:32:14]
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trpS [2018-05-30 14:32:14]

tryptophanyl-tRNA synthetase
Locus
BSU11420
Isoelectric point
6.54
Molecular weight
37.04 kDa
Protein length
330 aa Sequence Blast
Gene length
990 bp Sequence Blast
Function
translation
Product
tryptophanyl-tRNA synthetase
Essential
yes
E.C.
6.1.1.2
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → Aminoacyl-tRNA synthetases
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    1,218,113 → 1,219,105

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • ATP L-tryptophan tRNA(Trp) = AMP diphosphate L-tryptophyl-tRNA(Trp) (according to Swiss-Prot)

    • Protein family

  • class-I aminoacyl-tRNA synthetase family (according to Swiss-Prot)

    • Structure

  • 3PRH (Val144Pro mutant) PubMed
  • 1BM2 (complex with tryptophan, Geobacillus stearothermophilus)
  • 1MAW (complex with ATP, Geobacillus stearothermophilus)

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    trpS
    Description
    PubMed

    Regulation

  • induced by tryptophan limitation (T-box) PubMed

    • Additional information

  • A ncRNA is predicted between trpS and oppA PubMed
  • the T-box RNA is degraded by RNase Y PubMed
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    References

    Reviews

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    Original publications

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