rpsN [2018-09-04 19:26:31]

ribosomal protein

Locus: BSU01290

Isoelectric point: 10.91

Molecular weight: 7.11 kDa

Protein length: 61 aa

Gene length: 183 bp

Function: translation

Product: ribosomal protein S14

Essential: yes

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Ribosomal proteins
• Groups of genes → Essential genes
• Groups of genes → Phosphoproteins → Phosphorylation on an Arg residue

Gene

Coordinates: 141,757 → 141,942

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• ribosomal protein S14P family (according to Swiss-Prot) Zinc-binding S14P subfamily (according to Swiss-Prot)

Paralogous protein(s)

• RpsNB

Modification

• phosphorylated on Arg-41 PubMed

Cofactors

• requires zinc for activity PubMed

Structure

• 5NJT (the ribosome) PubMed

Expression and Regulation

Operons

• Genes: rpsJ-rplC-rplD-rplW-rplB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ-rplN-rplX-rplE-rpsN-rpsH-rplF-rplR-rpsE-rpmD-rplO-secY-adk-map-ybzG-infA-rpmJ-rpsM-rpsK-S56-rpoA-rplQ
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed (two promoters, about 140bp and 200bp upstream of the start codon), in SigA regulon

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response

  Regulation

  • strongly repressed in response to glucose starvation in M9 medium PubMed
  • likely autorepression of operon expression upon binding of excess of one ribosomal protein to the untranslated region of the mRNA PubMed

  Additional information

  • term-seq has identified a potential novel regulatory RNA element (protein-dependent leader) including an intrinsic transcription terminator upstream of rpsJ PubMed

References

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