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pcrB
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pcrB

heptaprenylglyceryl phosphate synthase
Locus
BSU_06600
Isoelectric point
4.20
Molecular weight
24.94 kDa
Protein length
228 aa Sequence Blast
Gene length
687 bp Sequence Blast
Function
unknown
Product
heptaprenylglyceryl phosphate synthase
Essential
no
Synonyms
yerE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Lipid metabolism → Lipid metabolism/ other

    • Gene

    Coordinates
    718,622 719,308

    The protein

    Catalyzed reaction/ biological activity

  • production of heptaprenylglyceryl phosphate from heptaprenyl diphosphate and glycerol-1-phosphate PubMed
  • all-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate --> 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate (according to UniProt)

    • Protein family

  • GGGP/HepGP synthase family (single member, according to UniProt)

    • Structure

  • 1VIZ PubMed

    • Expression and Regulation

    Operons

    Genes
    pcrB-pcrA-ligA-yerH
    Description
    PubMed

    Regulatory mechanism

  • LexA: repression, PubMed, in LexA regulon

    • Regulation

  • induced by DNA damage (LexA) PubMed
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    Biological materials

    Mutant

  • MGNA-A926 (yerE::erm), available at the NBRP B. subtilis, Japan
  • BKE06600 (pcrB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGTCATACGTTCCTCCAT, downstream forward: _UP4_TAGTAAATTGTACGGATTTG
  • BKK06600 (pcrB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGTCATACGTTCCTCCAT, downstream forward: _UP4_TAGTAAATTGTACGGATTTG

    • References

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