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stoA [2019-09-04 10:36:22]
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stoA [2019-09-04 10:36:22]

thiol-disulfide oxidoreductase, with thioredoxin-like domain, required for the synthesis of the endospore peptidoglycan cortex
Locus
BSU_13840
Isoelectric point
5.30
Molecular weight
18.66 kDa
Protein length
165 aa Sequence Blast
Gene length
498 bp Sequence Blast
Function
spore cortex formation, maturation of SpoVD in the forespore outer membrane
Product
thiol-disulfide oxidoreductase
Essential
no
Synonyms
spoIVH,ykvV
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    1,450,638 1,451,135

    The protein

    Catalyzed reaction/ biological activity

  • reduction of intramolecular disulfide bonds in SpoVD in the forespore outer membrane PubMed

    • Protein family

  • Thioredoxin family (according to UniProt)

    • Paralogous protein(s)

  • YneN, ResA

    • Structure

  • 3ERW PubMed

    • Localization

  • forespore envelope PubMed

    • Expression and Regulation

    Operons

    Genes
    ykvU-stoA
    Description
    PubMed

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
  • SigG: sigma factor, PubMed, in SigG regulon

    • Regulation

  • expressed during sporulation (SigE, SigG) PubMed

    • Additional information

  • A ncRNA is predicted between 'stoA' and 'zosA' PubMed
    • view in new tab

    Genes
    stoA
    Description
    PubMed

    Regulation

  • expressed during sporulation (SigE, SigG) PubMed

    • Additional information

  • A ncRNA is predicted between 'stoA' and 'zosA' PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B328 (ykvV::erm), available at the NBRP B. subtilis, Japan
  • 1S130 ( stoA::cat), PubMed, available at BGSC
  • 1S131 ( stoA::tet), PubMed, available at BGSC
  • BKE13840 (stoA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGAATCTTCCTTTCATG, downstream forward: _UP4_TAGCTGAGAGCATAGACTCT
  • BKK13840 (stoA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGAATCTTCCTTTCATG, downstream forward: _UP4_TAGCTGAGAGCATAGACTCT

    • Labs working on this gene/protein

  • Lars Hederstedt, University of Lund, Sweden Homepage

    • References

    Reviews

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    Original Publications

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