thiol-disulfide oxidoreductase, with thioredoxin-like domain, required for the synthesis of the endospore peptidoglycan cortex
function
spore cortex formation
product
thiol-disulfide oxidoreductase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SigG regulon]Gene
Coordinates on the chromosome (coding sequence)
1,450,638 -> 1,451,135
The protein
Catalyzed reaction/ biological activity
reduction of intramolecular disulfide bonds in [SW|SpoVD] [Pubmed|19919673]Protein family
thioredoxin domain (according to Swiss-Prot)Structure
[PDB|3ERW][SW|Localization]
forespore envelope [Pubmed|19919673]Expression and Regulation
Operon
''[protein|search|ykvU]-[protein|search|stoA]'' [Pubmed|15292147]''[protein|search|stoA]'' [Pubmed|15292147][SW|Sigma factor]
''[protein|search|ykvU]'': [protein|search|SigE] [Pubmed|12662922]''[protein|search|stoA]'': [protein|search|SigG] [Pubmed|15292147]Regulation
expressed during sporulation ([protein|search|SigE], [protein|search|SigG]) [Pubmed|12662922,15292147]Additional information
A [protein|search|ncRNA] is predicted between '[protein|search|stoA]' and '[protein|search|zosA]' [PubMed|20525796]Biological materials
Mutant
1S130 ( ''stoA''::''cat''), [Pubmed|15342593], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S130&Search=1S130 BGSC]1S131 ( ''stoA''::''tet''), [Pubmed|15342593], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S131&Search=1S131 BGSC]Labs working on this gene/protein
[SW|Lars Hederstedt], University of Lund, Sweden [http://www.cob.lu.se/microbiology/heme.html Homepage]References
Reviews
Original Publications
12662922,15292147,15342593,19144642,19919673,20525796 
