murJ [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

lipid II flippase

Locus: BSU30050

Isoelectric point: 10.00

Molecular weight: 59.00 kDa

Function: export of lipid II

Product: lipid II flippase

Essential: no

Synonyms: ytgP

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of peptidoglycan
• Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of peptidoglycan
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• cell wall synthesis, biosynthesis of cell wall components, membrane proteins

Gene

Coordinates on the chromosome (coding sequence): 3,073,531 -> 3,075,165

Phenotypes of a mutant

• an amj murJ double mutant is not viable PubMed
• a sigM murJ double mutant is not viable (due to the lack of both lipid II flippases) PubMed
• mutants lacking MurJ produce long cells and chains of cells PubMed

The protein

Protein family

• MOP exporter family

Paralogous protein(s)

• SpoVB, YabM, YkvU

References

Reviews

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Original Publications

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