SubtiBank SubtiBank
glpX [2017-8-11 16:0:3]
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glpX [2017-8-11 16:0:3]

class II fructose-1,6-bisphosphatase, gluconeogenesis
locus
BSU37090
pI
5.07
mw
33.80 kDa
protein length
321 aa Sequence Blast
gene length
963 bp Sequence Blast
function
gluconeogenesis
product
class II fructose-1,6-bisphosphatase
essential
no
ec
3.1.3.11
synonyms
ywjI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.2|Gluconeogenesis]

    • Gene

    Coordinates
    3,805,090 → 3,806,055

    The protein

    Catalyzed reaction/ biological activity

  • D-fructose 1,6-bisphosphate ==> D-fructose 6-phosphate + Pi

    • Protein family

  • FBPase class 2 family (according to Swiss-Prot)

    • Kinetic information

  • K(M) for FBP: 20 µM [Pubmed|19270101]

    • Structure

  • [PDB|3D1R] (from ''E. coli'', 49% identity, 68% similarity)[Pubmed|19073594]

    • Expression and Regulation

    Operons

    genes
    [gene|523B01B5E7141C7DFC28CE67EB92580F49C20844|murAB]-[gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]
    description
    [Pubmed|19270101]

    regulation

  • constitutive [Pubmed|19270101]
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    Biological materials

    Mutant

  • MGNA-B658 (ywjI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1657 NBRP B. subtilis, Japan]

    • References

  • 19270101,19073594