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murD [Mon Aug 31 2015 13:54:10 GMT+0200 (CEST)]
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
function
peptidoglycan precursor biosynthesis
product
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes]Gene
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (according to Swiss-Prot)Protein family
murCDEF family (according to Swiss-Prot)[SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|murE]-[protein|search|mraY]-[protein|search|murD]-[SW|spoVE]-[protein|search|murG]-[protein|search|murB]-[SW|divIB]-[protein|search|ylxW]-[protein|search|ylxX]-[protein|search|sbp]'' [Pubmed|1391053]Regulation
expressed during vegatative growth [Pubmed|1391053]References
