patA [Tue Nov 08 2016 11:20:39 GMT+0100 (CET)]

aminotransferase

locus: BSU14000

pI: 6.00

mw: 43.00 kDa

function: biosynthesis of lysine and peptidoglycan

product: aminotransferase

essential: yes

ec: 2.6.1.-

synonyms: uat

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.6|Biosynthesis/ acquisition of lysine/ threonine]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|cell wall synthesis], [SW|biosynthesis/ acquisition of amino acids], [SW|Biosynthesis of cell wall components], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 1,471,857 -> 1,473,038

Phenotypes of a mutant

• essential [Pubmed|23109554]

The protein

Catalyzed reaction/ biological activity

• N-acetyl-2-amino-6-ketopimelate --> N-acetyl-L,L-2,6-diaminopimelate [Pubmed|24261876]

Protein family

• class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

References